Friday May 5th, 2017

Extraction, Separation and Purification Line

CabeceraLinea2
The extraction, separation and purification line allows separation of products by both centrifugation and filtration. It is also completed with a supercritical extraction plant, a cell disruptor and chromatography equipment. It includes equipment such as:

SUPERCRITICAL FLUID EXTRACTION SYSTEM

Model: SFE-1000.
Manufacturer: Thar.

Supercritical carbon dioxide extraction of solid and liquid samples. The system has a co-solvent pump and two separators with manual pressure control. The system is controlled through the software provided by Thar Technologies.
  • ▸ Maximum extraction pressure: 600 bar.
  • ▸ Operating temperature: up to 150°C.
  • ▸ CO2 flow: 20-200 g/min.
  • ▸ Maximum co-solvent flow: 10 mL/min.
  • ▸ Solid sample extractor volume: 1L.
  • ▸ Column for liquid samples.
  • ▸ Volume of separators: 500 mL.
Linea2ExtraccionSupercritica

CENTRIFUGAL SEPARATOR

Model: Clara 20.
Manufacturer: Alfa laval.

The Clara 20 centrifuge allows the clarification of liquids containing solids in suspension.
  • ▸ Maximum rotor speed: 9,000 rpm.
  • ▸ Feed flow: 4 m3/h.
  • ▸ Maximum feed/sediment density: 1,100/1,499 kg /m3.
Linea2ClarificadoraCentrifuga

MEMBRANE FILTRATION UNIT

Model: LabStak M20.
Manufacturer: Alfa laval.

Plate and frem unit for membrane microfiltration, ultrafiltration, nanofiltration and reverse osmosis processes.
  • ▸ Maximum pressure: 64 bar.
  • ▸ Maximum temperature: 60ºC.
  • ▸ Feeding flow: 5-24 L/min.
  • ▸ Maximum filtration area: 0,72 m2.
  • ▸ MF, UF, NF and OI membranes are available.
Linea2FiltracionMembranas

FPLC

Model: Äkta Pilot.
Manufacturer: Ge Healthcare.

High performance liquid chromatography system design to purify from milligrams to tens of grams of product. The system is suitable for process development, process scale-up and scaledown, and small scale production.
  • ▸ Isocratic flow: 4 to 400 ml/min (with gradient up to 800 ml/min).
  • ▸ Pressure: up to 20 bar.
Linea2FPLC

CEL DISRUPTOR

Model: TS Series.
Manufacturer: Constant System.

It allows the mechanical breakdown of cells allowing the release of intracellular components without the use of chemicals.
  • ▸ Maximum pressure: 2.72 kbar.
  • ▸ Maximun flow rate: 40 mL/min.
Linea2DisruptorCelular

ULTRACENTRIFUGE

Model: Optima L-100 XP.
Manufacturer: Beckmann Coulter.

Ultracentrifuge capable of generating 802.400 xg at a maximum speed of 100,000 rpm, enabling the separation of a large diversity of samples.
  • ▸ Available rotors: 90 Ti, 70 Ti, SW 55Ti.
  • ▸ Maximum speed: 100,000 rpm (according to rotor).
  • ▸ Maximum force-g: 802,400 xg (according to rotor).
  • ▸ Temperature: 0-40ºC.
Linea2Ultracentrifuga

HPLC

Model: 1200 Series.
Manufacturer: Agilent.

High performance liquid chromatography used to identify and quantify the components of a sample. The system is equipped with DAD and RID detectors.
  • ▸ Flow: 0,2-10 mL/min.
  • ▸ Maximum pressure: 40 MPa (up to 5 mL/min).
  • ▸ RID and DAD Detectors.
  • ▸ Injection volume: 0,1-100 µL.
Linea2HPLC